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Study Finds Structural Brain Alterations In Patients With Irritable Bowel Syndrome

Fri, 07/23/2010 - 03:00
A large academic study has demonstrated structural changes in specific brain regions in female patients with irritable bowel syndrome (IBS), a condition that causes pain and discomfort in the abdomen, along with diarrhea, constipation or both. A collaborative effort between UCLA and Canada's McGill University, the study appears in the July issue of the journal Gastroenterology...
Categories: Stomach Bloating News

A Guide For Vaccinating The IBD Patient; Findings On Impact Of Gluten-Free Diet In Adult Celiac Patients

Wed, 06/23/2010 - 03:00
A guide for vaccinating the Inflammatory Bowel Disease patient, and studies looking at the impact of a gluten-free diet on adults with celiac disease and the relationship between cognitive factors and treatment response in patients with functional bowel disorders, like IBS, are among the highlights of the June issue of The American Journal of Gastroenterology...
Categories: Stomach Bloating News

Lubiprostone Successfully Completes Phase 3 Efficacy Trial In Japanese Patients Suffering From Chronic Idiopathic Constipation

Thu, 06/10/2010 - 01:00
Sucampo Pharmaceuticals, Inc. (NASDAQ: SCMP) and Abbott (NYSE:ABT) today announced that a pivotal phase 3 clinical trial of lubiprostone for chronic idiopathic constipation (CIC) in Japanese patients met its primary endpoint with statistical significance and demonstrated a safety profile consistent with previously reported clinical lubiprostone data...
Categories: Stomach Bloating News

Salix Pharmaceuticals Announces NDA Submission For XIFAXAN550 For Treatment Of Non-Constipation Irritable Bowel Syndrome

Thu, 06/10/2010 - 01:00
Salix Pharmaceuticals, Ltd. (NASDAQ:SLXP) today announced that the Company has submitted an efficacy supplement to NDA 21-361 for XIFAXAN® (rifaximin) 550 mg tablets for the proposed indication of treatment of non-constipation irritable bowel syndrome (Non-C IBS) and IBS-related bloating...
Categories: Stomach Bloating News

Symptoms Of Digestive Disorders Alleviated By Probiotic Found In Breast Milk

Fri, 06/04/2010 - 01:00
New research published in the FASEB Journal suggests that Lactobacillus reuteri immediately affects nerves in the gut, explaining how probiotics work Here's another reason to breast feed your baby: Canadian researchers have discovered how a probiotic found in breastmilk reduces or eliminates painful cramping in the gut...
Categories: Stomach Bloating News

Narrow-Band Imaging A Useful Tool To Detect In Vivo Angiogenesis In IBD Patients

Fri, 05/21/2010 - 06:00
Angiogenesis plays a crucial role in neoplastic and non-neoplastic chronic inflammatory disorders, including inflammatory bowel diseases (IBD). Several reports have shown that blockade of angiogenesis in preclinical models of IBD is a promising new therapeutic approach. Visualize angiogenesis in vivo may represent the first step for such a therapeutic approach...
Categories: Stomach Bloating News

Can Choir Singing Improve Irritable Bowel Syndrome?

Wed, 05/19/2010 - 03:00
A Swedish investigation has compared choir singing and group discussion in irritable bowel syndrome in the current issue of Psychotherapy and Psychosomatics. Singing in a choir is very popular in the Nordic countries. This activity has been associated with increased longevity, and it induces feelings of relaxation and energy...
Categories: Stomach Bloating News

Rotavirus Vaccine Greatly Reduces Hospitalizations For Acute Gastroenteritis In Children

Sat, 05/15/2010 - 01:00
Vaccinating infants against rotavirus, a leading cause of severe diarrhea and dehydration among babies and young children, was associated with a dramatic decline in U.S. hospitalization rates for acute gastroenteritis. The findings appear in a study, now available online (http://www.journals.uchicago.edu/doi/abs/10.1086/652403), published in the June 1 issue of The Journal of Infectious Diseases...
Categories: Stomach Bloating News

Even The Most Severe Symptoms Rapidly Relieved By Self-Directed Behavioral IBS Treatment

Thu, 05/13/2010 - 06:00
Nearly one-third of patients with irritable bowel syndrome (IBS) who underwent a novel behavior treatment developed by a University at Buffalo behavioral scientist achieved significant relief within four weeks of beginning treatment...
Categories: Stomach Bloating News

Researchers Report Mild-Mannered Metabolic Helper Rushes To Fight Invading Viruses

Mon, 05/10/2010 - 03:00
Within cells, an ancient antiviral duo can deliver a one-two knockout to thwart invading viruses, report researchers who have just unmasked the cellular sidekick that throws the first punch. The findings mean scientists must rethink the design of antiviral immunity and how the body fends off viruses of all types, including influenza and HIV...
Categories: Stomach Bloating News

Lexicon Presents Positive Outcome In IBS Patients Treated With LX1031 And Data Supporting Mechanism Of Action

Fri, 05/07/2010 - 03:00
Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX), a biopharmaceutical company focused on discovering and developing breakthrough treatments for human disease, presented results from its positive Phase 2 clinical study with LX1031 in patients with non-constipating irritable bowel syndrome (IBS) at Digestive Disease Week (DDW) 2010 in New Orleans, Louisiana...
Categories: Stomach Bloating News

Researchers Discover New Genetic Candidates For Irritable Bowel Syndrome

Wed, 05/05/2010 - 03:00
Most people associate serotonin with brain neurology, but over 95 percent of the body's serotonin occurs in the gastrointestinal tract, which has a complex neuronal circuit that has been called "the second brain" of the body. Now a Mayo Clinic research team has identified a number of genetic variants in serotonin genes that impact irritable bowel syndrome or IBS...
Categories: Stomach Bloating News

Ironwood And Forest Present Positive Linaclotide Results From Two Pivotal Phase 3 Trials In Patients With Chronic Constipation

Wed, 05/05/2010 - 03:00
Ironwood Pharmaceuticals, Inc. (NASDAQ: IRWD) and Forest Laboratories, Inc. (NYSE: FRX) presented Phase 3 clinical trial results assessing the efficacy and safety of the investigational drug linaclotide in patients with chronic constipation (CC)...
Categories: Stomach Bloating News

Antibiotic Prevents IBS Symptoms For Weeks After Final Dose

Wed, 05/05/2010 - 01:00
A targeted antibiotic provides effective and long-lasting relief of Irritable Bowel Syndrome symptoms, according to the results of two multisite Phase III clinical trials designed by Cedars-Sinai researchers. Rifaximin is the first drug treatment for IBS that relieves symptoms while it's being administered and continues to benefit patients after they stop taking the drug...
Categories: Stomach Bloating News

Patients With IBS Commonly Use Narcotics

Tue, 05/04/2010 - 04:00
Doctors often unnecessarily treat irritable bowel syndrome (IBS) with narcotics, according to a study led by University of North Carolina at Chapel Hill researchers. "This course of treatment is generally inadvisable because it does not improve functional status and may have adverse long term effects," said study lead author Spencer D...
Categories: Stomach Bloating News

Albireo Announces Positive Results From A Study With A3309 In Patients With Chronic Constipation

Fri, 04/30/2010 - 04:00
Albireo announced that additional clinical data will be reported from a recent study assessing the safety, tolerability and efficacy of A3309 in patients with chronic constipation. A3309 is a first-in-class investigational compound for the treatment of irritable bowel syndrome with constipation (IBS-C) and chronic constipation (CC)...
Categories: Stomach Bloating News

Outstanding Young Gastroenterologists Receive AGA Foundation 2010 Research Scholars Award

Thu, 04/29/2010 - 01:00
The Foundation for Digestive Health and Nutrition (FDHN) has announced the 2010 American Gastroenterological Association (AGA) Foundation research scholars. The grants have been awarded to seven outstanding young gastroenterologists who promise to make significant strides in the field of gastrointestinal research...
Categories: Stomach Bloating News

Severe IBS Symptoms Relieved By Non-Medical Treatment

Wed, 04/28/2010 - 06:00
A significant proportion of irritable bowel syndrome (IBS) patients treated with cognitive behavior therapy have a positive response within four weeks of treatment, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association (AGA) Institute...
Categories: Stomach Bloating News

Ironwood And Forest To Present Linaclotide Phase 3 Chronic Constipation Data

Wed, 04/28/2010 - 02:00
Ironwood Pharmaceuticals, Inc. (NASDAQ: IRWD) and Forest Laboratories, Inc...
Categories: Stomach Bloating News
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